Systematic Review Finds Cruciferous Vegetable Intake Linked to Reduced Risk of Multiple Cancers
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@EBSCO
Summary
This systematic review and dose-response meta-analysis of 226 epidemiological studies examines the relationship between cruciferous vegetable intake (broccoli, cauliflower, cabbage) and various cancers. Higher consumption is linked to reduced risk of colorectal, lung, upper gastrointestinal, gynecological (ovarian and endometrial), bladder, renal, and prostate cancers, with specific intake thresholds identified (3-7.4 servings per week). Regional differences were found: stronger associations with lung cancer, HNSCC, and esophageal cancer in Asian populations, while colorectal, renal, gynecological, and prostate cancers showed stronger associations in American populations. The protective effect is most significant within 2-15 years of follow-up.
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Key quotes
· 3 pulledHigher consumption of cruciferous vegetables—such as broccoli, cauliflower, and cabbage—is generally linked to a reduced risk of several cancers, including colorectal, lung, upper gastrointestinal, gynecological (ovarian and endometrial), bladder, renal, and prostate cancers
The study also highlights regional differences, noting stronger associations with lung cancer, head and neck squamous cell carcinoma (HNSCC), and esophageal cancer in Asian populations
The protective effect appears most significant within 2 to 15 years of follow-up, emphasizing the influence of intake level, cancer type, geographic region, and duration on the relationship between cruciferous vegetables and cancer risk
This meta-analysis systematically reviews 226 epidemiological case-control and cohort studies to examine the association between cruciferous vegetable intake and various cancers. It finds that higher consumption of cruciferous vegetables—such as brocco
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