Study: Most Patients Regain Weight and Lose Health Benefits After Stopping GLP-1 Drugs
By
voxadam
Soft in all the wrong places. Take with a strong tea.
Summary
A study on tirzepatide (a GLP-1 drug) found that after stopping the medication, 82% of participants regained at least 25% of the weight they had lost, with 57% regaining at least 50% and 24% regaining at least 75%. The weight regain was associated with reversal of cardiovascular and metabolic health improvements. However, 17.5% of participants did not experience significant weight regain, suggesting individual variability in response to drug withdrawal.
Key quotes
· 3 pulledOf the 308 who benefited from tirzepatide, 254 (82 percent) regained at least 25 percent of the weight they had lost on the drug by week 88.
Generally, the more weight people regained, the more their cardiovascular and metabolic health improvements reversed.
On the other hand, there were 54 participants of the 308 (17.5 percent) who didn't regain a significant amount of weight (less than 25 percent.)
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