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Protein phosphatase 2A regulates senescence and immunogenicity in medulloblastoma models

Medulloblastoma (MB) is the most common malignant pediatric brain tumor. Current therapies are associated with substantial morbidity, and prognosis remains poor in high-risk subgroups, particularly…

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Proteomic and phosphoproteomic profiling reveals melanoma cell responses to T cell attack

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PHD1-dependent hydroxylation of RepoMan (CDCA2) on P604 modulates the control of mitotic progression

Prolyl-hydroxylases (PHDs) are oxygen-sensing enzymes that mediate the hydroxylation of proline residues. In mammals, three PHD isoforms (PH

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