Phages redirect vaccine immunity to attack cancer cells in mouse study
By
Tom Bawden
Summary
Researchers have demonstrated a novel approach to cancer treatment by using bacteriophages (viruses that infect bacteria) to redirect vaccine-induced immunity toward cancer cells. In mouse studies, vaccinating against malaria and then using a harmless phage to direct that immune response toward tumors resulted in nearly half of the animals having their tumors eradicated. This approach could potentially help more people benefit from immunotherapy, which currently doesn't work for many patients.
Source
Twitter / XPhages redirect vaccine immunity to attack cancer cells in mouse studynewscientist.comKey quotes
· 3 pulledVaccinating mice against malaria and then using a harmless phage, a virus that infects bacteria, to direct that immune response towards cancer cells resulted in the tumours being eradicated in nearly half of the animals.
Immunotherapy, treatments that use our immune system to fight cancer, has transformed how we treat some forms of the condition, but many people still don't benefit.
Phages, viruses that infect bacteria, could be genetically manipulated to destroy cancerous cells using the immunity we have acquired from vaccines
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