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Meflin confers antifibrotic properties to intestinal fibroblasts in inflammatory bowel disease

Dysfunctional intestinal fibrosis is an irreversible complication of Crohn’s disease (CD). The complex heterogeneity of intestinal mesenchymal cells makes it difficult to understand the pathogenesis…

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Multi-model transcriptomic atlas reveals shared inflammatory programs and epithelial-immune crosstalk in chronic colitis

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The role of MSCs in the IL23/17 pathway and their response to mechanical stress

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Selective ROCK2 inhibitor TDI01 shows anti-fibrotic potential in liver fibrosis preclinical and clinical studies

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Milk-derived extracellular vesicles attenuate pre-inflammatory bowel disease via Lactobacillus murinus-mediated TLR2 signaling modulation

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ROCK2 in liver endothelial cells identified as key driver of fibrosis with early clinical translation potential

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