Mechanistic insights into transcriptional regulation of ARHGAP36 expression identify a factor predictive of neuroblastoma survival
Cancer repeatedly exploits attributes fundamental for morphogenesis to advance malignancy and metastasis. This is illustrated by lineage-specific transcription factors that regulate neural crest…
Read the full articleYou might also wanna read
Epigenetic control of BMP signaling in dental mesenchyme directs sensory nerve growth during organ development
Sensory innervation of developing organs is influenced by molecular cues secreted from surrounding tissues, yet the mechanisms coordinating
pnas.org·7d ago
ChEA-KG: A network-based transcription factor enrichment analysis tool with time-series workflow capabilities
Abstract. Transcription factor (TF) modules interact to regulate key biological processes and cell-state transitions in normal physiology an
doi.org·16d ago
ETS1 Identified as Dual Driver of Metastasis and Immune Evasion in Squamous Cell Carcinoma
Abstract. Transcriptional intratumoral heterogeneity (ITH) is a hallmark of aggressive cancers. Investigation into the ITH programs that dri
aacrjournals.org·1mo ago
ZNF274 constrains lineage plasticity and drives intrinsic resistance to CDK7 inhibitors in pancreatic cancer
ZNF274 limits pancreatic cancer plasticity by maintaining chromatin and suppressing genes. Loss of ZNF274 shifts from classical to invasive
Científicos financiados por los Institutos Nacionales de la Salud descubren pistas sobre las lesiones precancerosas y la biología tumoral
En nuevos estudios publicados por la Red del Atlas de Tumores Humanos (HTAN) del Instituto Nacional del Cáncer (NCI), se explora la función
SAM68 functions as a multifunctional post-transcriptional regulator in cardiomyocyte differentiation
Abstract. RNA-binding proteins (RBPs) of the STAR family play key roles in mammalian development, yet their contributions to lineage specifi
doi.org·1mo ago
Comments
Sign in to join the conversation.
No comments yet. Be the first.