JAMA Study: Teen Marijuana Use Doubles Risk of Psychosis and Bipolar Disorder
A landmark JAMA Health Forum study of 463,396 adolescents aged 13-17 found that teen marijuana use more than doubles the risk of developing psychotic disorders and bipolar disorder by young adulthood (age 26). Using electronic health records from Kaiser Permanente Northern California, researchers found that cannabis use typically preceded psychiatric diagnosis by 1.7-2.3 years. This is one of the largest longitudinal studies ever conducted on adolescent cannabis use and mental health outcomes.
Key quotes
A landmark population study involving nearly half a million teenagers has found that adolescent marijuana use is associated with more than double the risk of developing two of the most serious mental illnesses known — psychotic disorders and bipolar disorder — by young adulthood.
The research, published in JAMA Health Forum on February 20, 2026, tracked 463,396 adolescents aged 13 to 17 through age 26 using electronic health record data from Kaiser Permanente Northern California.
It represents one of the largest longitudinal studies of its kind ever conducted on adolescent cannabis
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