Study: Imaging scans detect prostate cancer progression missed by stable PSA levels
A new analysis led by researchers at Weill Cornell Medicine and Duke University, published in the Journal of Clinical Oncology, found that advanced prostate cancer patients may need periodic imaging scans to detect tumor progression even when PSA (prostate-specific antigen) levels remain stable or are undetectable. The study analyzed data from over 2,500 men in two multinational phase 3 clinical trials, revealing that relying solely on PSA monitoring can miss cancer progression. This challenges the standard practice of using PSA levels as the primary indicator for disease advancement in advanced prostate cancer patients.
Key quotes
Patients with advanced prostate cancer may need periodic imaging scans to catch tumor growth even with stable levels of prostate-specific antigen (PSA)
In some cases, cancer progression was detected on scans even when PSA levels were undetectable
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