Study: Expanded Diagnostic Criteria May Explain Rise in ADHD and Autism Diagnoses
By
Megan Brooks
Summary
A population-based cohort study in Denmark (1994-2016) involving over 37,000 individuals found that those diagnosed with autism spectrum disorder (ASD) or ADHD in recent years carried a lower genetic burden (lower polygenic scores) than those diagnosed decades ago. For every 10-year increase in diagnosis year, mean polygenic scores declined by 0.07 SDs for ASD and 0.06 SDs for ADHD. This suggests that expanded diagnostic criteria—not just increased awareness or environmental factors—may account for much of the rise in diagnoses, as milder cases with lower genetic loading are now being identified.
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Key quotes
· 3 pulledIn this cohort study, we found a decre
For every 10-year increase in diagnosis year, mean polygenic scores declined by 0.07 SDs for ASD and 0.06 SDs for ADHD
The population-based cohort study included 17,071 individuals with ASD and 20,111 with ADHD diagnosed in Denmark from 1994 to 2016
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