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Cryo-EM structures reveal how Wnt proteins assemble with Frizzled and LRP6 receptors to activate signaling

Cryo-EM structures of Wnt3a/Fzd8-CRD/LRP6-E3E4 reveal assembly and activation mechanisms of the Wnt signalosome extracellular complex.

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Correcting congenital myasthenia-associated acetylcholine receptor defects

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Canonical and phosphoribosyl ubiquitination coordinate to stabilize a proteinaceous structure surrounding the Legionella -containing vacuole

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