Geothermal Amoeba Sets New Upper Temperature Limit for Eukaryotes at 63°C
By
wjb3
Fresh out the oven, still warm. Top of the tray.
Summary
Researchers have discovered a novel geothermal amoeba, Incendiamoeba cascadensis, that divides at 63°C (145.4°F), establishing a new record for the upper temperature limit across all eukaryotes. The study used growth experiments, expansion microscopy, and high-temperature live-cell imaging to demonstrate cellular proliferation and movement up to 64°C. Genome analysis revealed enrichment of genes related to proteostasis, genome stability, and environmental sensing. This discovery challenges current paradigms about temperature constraints on eukaryotic cells and expands understanding of where eukaryotic life can persist.
Key quotes
· 4 pulledWe isolated a novel geothermal amoeba, Incendiamoeba cascadensis, that divides at 63°C (145.4°F), establishing a new record for the upper temperature limit across all eukaryotes.
Using high-temperature live-cell imaging, we quantified movement up to 64°C.
We assembled the genome of I. cascadensis and using comparative genomics found an enrichment of genes related to proteostasis, genome stability, and sensing the external environment.
Taken together, our findings challenge the current paradigm of temperature constraints on eukaryotic cells and reshape our understanding of where and how eukaryotic life can persist.
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