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Genetically targeted photocatalytic organic dyes for spatiotemporally controlled organic synthesis in specific living cells

By

Zhenan Bao

14h agoen

Source

Nature ChemistryGenetically targeted photocatalytic organic dyes for spatiotemporally controlled organic synthesis in specific living cellsnature.com
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Nature Chemistry, Published online: 08 July 2026; doi:10.1038/s41557-026-02195-6 Adapting abiotic catalysis to living cells broadens the scope of in situ non-natural synthesis, but it is challenging to achieve synthetic versatility at cellular-level spatiotemporal organization. Now organic dyes have been shown to perform light- and genetically patternable photocatalytic synthesis, enabling in situ C–H functionalization and the construction of ligands for protein translocation.

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