Dynamic regulation of origin firing factors links CDK activity to dormant origin activation

Cdh1 stabilizes STING to boost innate immune activation in renal cell carcinoma, study finds

This article presents research by Zhu et al. on the role of the APC/C adaptor protein Cdh1 in stabilizing STING (a key innate immune sensor)

Cell- and tissue-specific regulation of immune responses by IL-17 cytokine signaling

This article reviews recent advances in understanding the cell- and tissue-specific activities of IL-17 family cytokines, which are central

Cysteine depletion triggers adipose tissue thermogenesis and weight loss

Gemma-Based AI Model Identifies Potential Cancer Therapy Pathway Through Conditional Immune Amplification

Researchers used a new 27 billion parameter foundation model called C2S-Scale 27B, built on Google's Gemma family of open models, to discove

Efficient mRNA delivery to resting T cells to reverse HIV latency

Method to reverse cellular ageing is about to be tested in humans