Dodging the cytokine storm: Delivering ASOs without adverse effects

Manufacturing and regulatory hurdles threaten cell and gene therapy progress

The article discusses how manufacturing and regulatory challenges are hindering the progress of cell and gene therapies, particularly in can

Next-generation immune models: bioinks, 3D bioprinting, and future directions

Monoallelic PSMB8 variants cause immunodeficiency and autoinflammation through impaired immunoproteasome assembly

This study identifies seven individuals from five unrelated families carrying five distinct monoallelic PSMB8 variants that cause proteasome

Study reveals molecular mechanism linking statins to muscle side effects via NLRP3 inflammasome and protein-prenylation pathway

This scientific research article investigates the molecular mechanisms behind statin-associated myopathy (muscle side effects). The study fi

Trodelvy's FDA Approval Highlights Cybersecurity Risks in Healthcare Data Infrastructure

The article examines the cybersecurity vulnerabilities exposed by the FDA approval of Trodelvy (sacituzumab govitecan) for metastatic triple

Efficient mRNA delivery to resting T cells to reverse HIV latency