Congratulations to the Michelle Chang Lab, publishing “Targeted enzyme discovery using metal-coordination mining” today in @Nature. Great work from Yanni and Michelle. Full paper

Global protein-ligand binding affinity profiling via photocatalytic labeling

EnzymeMiner 2.0: an automated bioinformatics tool for enhanced enzyme discovery and property analysis

This article presents EnzymeMiner 2.0, an updated bioinformatics tool for automated discovery and analysis of enzymes from protein sequence

Reflections on 2024 Bio-ML Predictions: Generative Chemistry and Molecular Dynamics Challenges

The article reflects on the author's 2024 predictions about bio-ML (biological machine learning) from a 2026 perspective, focusing on genera

Large-scale discovery, analysis and design of protein energy landscapes

https://doi.org/10.1126/science.aed8713

Qt45: A small polymerase ribozyme that can synthesize itself