Sea cucumber tissue explants demonstrate sustained survival and growth for over 3 years in natural seawater
By
Annie Mercier
Summary
This scientific research paper reports the discovery that explanted tissues (epidermal, connective, neural, and muscle) from the sea cucumber Psolus fabricii can survive, heal, and continue growing in natural seawater without any supplementation for over 3 years. These tissue explants, termed LiPfe (living immortal P. fabricii explants), displayed immune activity, cell cycling, and tissue reorganization, challenging the biological paradigm that lost and discarded tissues have a terminal fate. The study demonstrates a form of natural tissue immortality in a deuterostome species.
Source
Twitter / XSea cucumber tissue explants demonstrate sustained survival and growth for over 3 years in natural seawaterscim.agKey quotes
· 4 pulledSenescence and immortality are central biological paradigms.
While regenerative capabilities in Deuterostomia are known, the fate of lost and discarded tissues has been presumed terminal.
Here, we demonstrate that explanted epidermal, connective, neural, and muscle tissue from the sea cucumber Psolus fabricii... healed and continued to grow in natural, nonaxenic seawater without supplementation for more than 3 years.
These explants, termed LiPfe (living immortal P. fabricii explants) displayed immune activity, cell cycling, tissue reorganization.
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