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Arrayed single-gene perturbations identify drivers of human anterior neural tube closure

Genetic studies of human embryonic morphogenesis are constrained by ethical and practical challenges, restricting insights into developmental mechanisms and disorders. Human pluripotent stem cell…

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Single-cell multi-omic atlas and morphogen screening informs midbrain and hindbrain organoid engineering

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Mapping of the Developmental Atlas of the Visual System and Research on Embryonic Neurogenesis Phenomena

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Single-cell atlas reveals asynchronous development of human meninges layers during early-to-mid gestation

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D-SPIN: A computational framework for modeling gene regulatory networks from single-cell perturbation data

D-SPIN is a computational framework for constructing mechanistically interpretable, generative models of cellular regulatory networks from s

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ChEA-KG: A network-based transcription factor enrichment analysis tool with time-series workflow capabilities

Abstract. Transcription factor (TF) modules interact to regulate key biological processes and cell-state transitions in normal physiology an

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