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AI Foundation Model Improves Ophthalmologist Diagnostic Accuracy in Randomized Controlled Trial

By

jameslk

9mo ago· 23 min readenInsight

Summary

Researchers developed EyeFM, a multimodal vision-language eyecare foundation model trained on 14.5 million ocular images from global datasets. In a randomized controlled trial with 668 participants and 16 ophthalmologists, the AI copilot significantly improved diagnostic accuracy (92.2% vs 75.4%), referral rates (92.2% vs 80.5%), and patient compliance with follow-up recommendations. The study demonstrated that AI assistance can enhance ophthalmologist performance and patient outcomes in retinal disease screening.

Key quotes

· 4 pulled
Ophthalmologists with EyeFM copilot achieved higher correct diagnostic rate (92.2% versus 75.4%, P < 0.001) and referral rate (92.2% versus 80.5%, P < 0.001)
The intervention group demonstrated higher compliance with self-management (70.1% versus 49.1%, P < 0.001) and referral suggestions (33.7% versus 20.2%, P < 0.001) at follow-up
Our study provided evidence that implementing EyeFM copilot can improve the performance of ophthalmologists and the outcome of patients
Trained and validated on multimodal data from 14.5 million images from multicountry datasets, a foundation model is shown to increase diagnostic and referral accuracy of clinicians
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In the context of an increasing need for clinical assessments of foundation models, we developed EyeFM, a multimodal vision–language eyecare copilot, and conducted a multifaceted evaluation, including retrospective validations, multicountry efficacy valid

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