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AI Agents Demonstrate Autonomous Execution of High Energy Physics Analysis Pipelines

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[Submitted on 20 Mar 2026 (v1), last revised 20 Jun 2026 (this version, v3)]

3h ago· 2 min readenInsight

Summary

This paper presents a proof-of-concept demonstrating that large language model-based AI agents (specifically Claude Code) can autonomously execute substantial portions of a high energy physics (HEP) analysis pipeline, including event selection, background estimation, uncertainty quantification, statistical inference, and paper drafting. The authors introduce a framework called Just Furnish Context (JFC) that integrates autonomous analysis agents with literature-based knowledge retrieval and multi-agent review. They demonstrate this by conducting analyses on open data from ALEPH, DELPHI, and CMS, including a CMS Run1 Open Data H→τ+τ− measurement and the first Lund plane measurement on LEP data — a genuinely novel result produced autonomously by an AI agent. The authors argue the HEP community underestimates current AI capabilities and advocate for new strategies in training, analysis organization, and human expertise allocation.

Source

bskyAI Agents Demonstrate Autonomous Execution of High Energy Physics Analysis Pipelinesarxiv.org

Key quotes

· 5 pulled
Large language model-based AI agents are now able to autonomously execute substantial portions of a high energy physics (HEP) analysis pipeline with minimal expert-curated input.
We argue that the experimental HEP community is underestimating the current capabilities of these systems, and that most proposed agentic workflows are too narrowly scoped or scaffolded to specific analysis structures.
We present a proof-of-concept framework, Just Furnish Context (JFC), that integrates autonomous analysis agents with literature-based knowledge retrieval and multi-agent review, and show that this is sufficient to plan, execute, and document a credible high energy physics analysis.
We demonstrate this by conducting analyses on open data from ALEPH, DELPHI, and CMS to perform electroweak, QCD, and Higgs boson measurements.
Rather than replacing physicists, these tools promise to offload the repetitive technical burden of analysis code development, freeing researchers to focus on physics insight, truly novel method development, and rigorous validation.
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Large language model-based AI agents are now able to autonomously execute substantial portions of a high energy physics (HEP) analysis pipeline with minimal expert-curated input. Given access to a HEP dataset, an execution framework, and a corpus of prior

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