Chromatin landscape and epigenetic heterogeneity of acute myeloid leukaemia
Nature, Published online: 08 July 2026; doi:10.1038/s41586-026-10703-4 An ATAC-seq-based approach is used to classify acute myeloid leukaemia (AML) into 16 epigenomic subgroups, and provides insight into the role of non-genetic mechanisms in determining pathogenesis, clinical behaviour and drug sensitivity in this disease.
