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Enzymatic Synthesis of Oligopeptide
How do you get peptides into cells?
FDA-approved Trofinetide for Rett Syndrome
Commonly Used Condensation Agents in Peptide Solid Phase Synthesis
Peptide synthesis, particularly solid-phase peptide synthesis (SPPS), is a widely employed method for creating peptides of varying lengths and sequences. The process has revolutionized the ability to produce synthetic peptides ...
Most Commonly Used Peptides in Cosmetics
Antitumor Peptides: Mechanisms, Production, and Applications
In recent years, anti-tumor peptides have emerged as a research hotspot in the biomedical field due to their unique molecular properties and broad therapeutic potential. Compared to traditional chemotherapy drugs, ...
Representative Peptides for In Vivo Imaging
The biological activity of peptides is regulated through their binding to corresponding receptors. Peptides that target receptors overexpressed on tumor cells—but not on normal cells—are excellent candidates for in vivo tumor ...
Cell-penetrating Peptides (CPPs) Used in Drug Delivery Systems
The cell membrane is a natural barrier composed of a lipid bilayer, which restricts the entry of external substances into the cell and ensures the stability of the intracellular environment. ...
Progress in Macrocyclic Peptide Drug Development
The cyclic structure of macrocyclic peptides not only confers high binding affinity and molecular stability but also overcomes key challenges faced by traditional peptides, such as enzymatic degradation and low oral ...
Fundamentals of Modern Peptide Synthesis
“Peptide synthesis” encompasses the preparation of a wide range of substances, from simple small-molecule peptides to large proteins. Bruce Merrifield’s pioneering introduction of solid-phase peptide synthesis (SPPS) fundamentally transformed peptide synthesis strategies ...