Non-genotoxic transplantation and in vivo selection through epitope editing
Nature, Published online: 08 July 2026; doi:10.1038/s41586-026-10737-8 Epitope editing of KIT enables antibody-based, non-genotoxic conditioning that selectively enriches therapeutic BCL11A-edited haematopoietic stem/progenitor cells, supports durable engraftment, preserves clonal diversity and enhances induction of fetal haemoglobin, a therapeutic approach
