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Novel troponin T assay could double the rapid rule-out of myocardial infarction in EDs
hs-cTnTA sixth-generation high-sensitivity cardiac troponin T (hs-cTnT) assay could enable clinicians to safely rule out myocardial infarction in more than twice as many patients with a single blood test, potentially reducing hospital admissions and emergency department (ED) challenges, according to a multinational cohort study. Chest pain and related sympto
Mesh placement linked to recurrence and bowel obstruction risk after ventral hernia repair
Retromuscular mesh placement and intraperitoneal onlay mesh (IPOM) are associated with higher risks of reoperation for recurrence and bowel obstruction following primary ventral hernia repair compared with onlay placement, according to recent Danish research. Mesh reinforcement is widely regarded as the standard approach for primary ventral hernia repair, bu
Digital platforms and artificial intelligence: view from EULAR 2026
Artificial intelligence and digital health platforms have the potential to support patient education, shared decision-making and engagement across rheumatic and musculoskeletal diseases, as research presented at the European Alliance of Associations for Rheumatology Congress 2026 highlights. Health literacy remains a key determinant of outcomes in rheumatic
RSV rapidly rebounded in European infants after Covid-19, meta-analysis finds
Respiratory syncytial virus (RSV) rapidly re-emerged as the leading cause of respiratory viral infection among European infants after Covid-19 restrictions were lifted, according to a systematic review and meta-analysis, which also revealed that common respiratory viruses recovered at markedly different rates post-pandemic. Published in the European Journal
Supporting patients with RMDs to optimise the gut microbiome: tips from EULAR 2026
Three expert speakers from the EULAR Congress 2026 share their top tips for where to start when supporting patients with rheumatic and musculoskeletal diseases to enhance their gut microbiome and help to reduce inflammation and other symptoms. The gut microbiome is a subject well and truly in vogue and the associated wellness industry is thriving […] The pos
Clinical benefit of vitamin D and calcium supplements for fracture prevention questioned
Calcium, vitamin D or combined supplementation provide little to no clinically meaningful benefit for preventing fractures or falls in adults, according to new study, challenging the routine use of these supplements for musculoskeletal health. Falls and fragility fractures remain a major cause of morbidity in older adults, with around a third of people aged
Risankizumab outperforms deucravacitinib in moderate psoriasis, interim trial data show
Risankizumab produces greater clinical and patient-reported benefits than deucravacitinib in biologic-naive adults with moderate plaque psoriasis, according to preliminary findings from the IMMpactful trial. Choosing the optimal first-line systemic therapy for patients with moderate plaque psoriasis has become increasingly complex with the availability of ne
Post-diagnostic statin use and survival in hormone receptor-positive early breast cancer
Women with early hormone receptor-positive breast cancer who use statins after diagnosis have lower breast cancer-specific mortality than non-users, according to a large Finnish population study, with findings supporting further evaluation of statins as a potential adjunct to standard treatment. The population-based retrospective cohort study, published in t
Blood eosinophil count may identify preschool children at greater risk of wheeze attacks
Preschool children with elevated blood eosinophil count (BEC) are more likely to experience future wheeze attacks, while inhaled corticosteroids (ICS) are associated with lower short-term attack odds in those with eosinophilic or allergic disease, according to recent research. Predicting which preschool children with recurrent wheeze are most likely to exper
Bidirectional phenotype switching between psoriasis and atopic dermatitis characterised
Real-world evidence on the ‘flip-flop’ phenomenon between psoriasis and atopic dermatitis (AD) highlights the need for clinicians to recognise and appropriately manage treatment-associated phenotype switching. Psoriasis and AD have traditionally been viewed as distinct inflammatory skin diseases driven predominantly by type 17 and type 2 immune pathways, res
Respiratory oscillometry shows considerable potential for infant lung assessment
Respiratory oscillometry is a feasible, non-invasive method for assessing lung function in infants from birth to one year of age, with potential applications in neonatal intensive care, long-term respiratory monitoring and early identification of infants at risk of respiratory disease, according to the findings of a scoping review. Assessing lung function in
Shaping the future of cardio-oncology: insights from ESC Cardio-Oncology 2026 and beyond
From major gaps in cardio-oncology training to emerging evidence on cardioprotective therapies, ESC Cardio-Oncology 2026 showcased the rapid evolution of the speciality. Here, Andrea Porter explores key messages from the conference and considers how broader initiatives, such as the CARDIOCARE project, are helping to shape the future of cardiovascular care fo
Delgocitinib cream linked to low systemic exposure in chronic hand eczema, post hoc analysis shows
Delgocitinib cream resulted in minimal systemic exposure in adults with moderate-to-severe chronic hand eczema, including under maximal-use conditions, according to a recent post hoc analysis of the 2024 phase 3 DELTA 2 trial. Topical Janus kinase (JAK) inhibitors have expanded the treatment options for chronic inflammatory skin diseases, but systemic absorp
Evidence linking legume and soy intake with reduced hypertension risk strengthens
Greater consumption of legumes and soy foods is associated with a reduced risk of developing hypertension, according to a systematic review and dose–response meta-analysis that identified protective associations across prospective cohort studies. As hypertension remains the leading modifiable risk factor for the global disease burden and cardiovascular morbi
Nirsevimab linked to marked reduction in paediatric RSV hospitalisations, real-world study shows
Introduction of the monoclonal antibody nirsevimab in routine clinical practice is associated with a 51% reduction in respiratory syncytial virus (RSV)-related hospitalisations among children under two years of age, according to a real-world study conducted at a large German tertiary centre. RSV is one of the leading causes of hospitalisation in infants and
Generalisability of proposed clinical sepsis phenotypes questioned by international validation study
Four widely cited clinical sepsis phenotypes could not be consistently reproduced across independent cohorts, suggesting they may not yet be suitable for universal clinical use or for guiding precision medicine strategies, an analysis of more than 48,000 emergency department encounters has shown. Sepsis remains a major cause of morbidity and mortality worldw