How Wolbachia-infected mosquitoes could stop disease spread: Evidence from field trials
By
Angus Dalton
A second-rack bagel that's nearly first-rack. Tasty stuff.
Summary
The article discusses the World Mosquito Program's use of Wolbachia bacteria to combat mosquito-borne diseases. Wolbachia bacteria outcompete viruses like dengue, Zika, and chikungunya by consuming cholesterol that viruses need to survive, and also boost mosquitoes' immune systems. Field trials began in Cairns, Australia, and by 2021 a randomized controlled trial in Yogyakarta provided strong evidence of the technique's effectiveness. The article notes that Australia may need to replicate this approach with the arrival of a new aggressive mosquito species.
Key quotes
· 5 pulledScientists suspect the bacteria outcompete viruses within mosquitoes.
Both pathogens need cholesterol, for example, and if you've got a population of Wolbachia within mozzies hoovering up all the cholesterol, the viruses 'starve'.
The bacteria also turbocharge a mozzie's immune system, which helps repel viral infection.
Could Wolbachia-infected mosquitoes stop diseases spreading in the real world?
By 2021, the technique had its strongest evidence, with a randomised controlled trial in Yogyakarta
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