How Wolbachia-infected mosquitoes could stop the spread of viral diseases
By
Angus Dalton
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Summary
The article discusses the World Mosquito Program's use of Wolbachia bacteria to combat mosquito-borne viruses like dengue. Wolbachia bacteria outcompete viruses for resources (like cholesterol) inside mosquitoes and boost their immune systems, effectively starving and repelling viral infections. Field trials began in Cairns, Australia, and by 2021 a randomized controlled trial in Yogyakarta provided strong evidence of the technique's effectiveness. The article notes that Australia may need to replicate this approach due to the arrival of a new, aggressive mosquito species.
Key quotes
· 4 pulledScientists suspect the bacteria outcompete viruses within mosquitoes.
Both pathogens need cholesterol, for example, and if you've got a population of Wolbachia within mozzies hoovering up all the cholesterol, the viruses 'starve'.
The bacteria also turbocharge a mozzie's immune system, which helps repel viral infection.
By 2021, the technique had its strongest evidence, with a randomised controlled trial in Yogyakarta.
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