IISc Study Reveals How Single Gene Disruption Alters Serotonin Signaling and Social Behavior in Worms
By
rainhacker
Properly proved. Has structure, has flavour, has a point.
Summary
Researchers at the Indian Institute of Science have discovered that disrupting a single conserved synaptic gene in the worm Caenorhabditis elegans alters serotonin signaling, which affects social behavior. The study, led by Professor Kavita Babu and published in PNAS, reveals how specific genetic disruptions impact neuromodulatory pathways that regulate mood and social interactions, providing insights into the molecular mechanisms underlying social behavior.
Key quotes
· 4 pulledStudying social behaviour is crucial for understanding how certain neuromodulatory pathways – like the serotonin pathway, which influences mood and social interactions – are regulated.
Kavita Babu, Professor at the Centre for Neuroscience (CNS), Indian Institute of Science (IISc), and her lab have been investigating these signalling mechanisms using the worm Caenorhabditis elegans.
In a new study published in the Proceedings of the National Academy of Sciences, they report that the disruption of a single conserved synaptic gene alters the signalling of a s
IISc is the premier institute for advanced scientific and technological research and education in India.
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