CEDAR platform releases cancer-specific epitope prediction tools and analysis pipelines for immuno-oncology research
By
Carri, Ibel, Greenbaum, Jason, Yan, Zhen, Kim, Kevin, Kim, Haeuk, Premlal, Ashmitaa Logandha Ramamoorthy, Marrama, Daniel, Blazeska, Nina, Carter, Hannah, Lee, Ko-Han, Sears, Timothy, Nielsen, Morten, Sette, Alessandro, Peters, Bjoern, Koşaloğlu-Yalçın, Zeynep
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Summary
The article describes the Cancer Epitope Database and Analysis Resource (CEDAR), a platform developed to address the challenge of accurately identifying immunogenic cancer epitopes in immuno-oncology. It provides comprehensive curation of experimentally validated epitopes and has released a suite of cancer-specific computational tools and analysis pipelines via the nextgen-tools.iedb.org platform, enabling users to generate, evaluate, and prioritize candidate T cell epitopes for cancer research.
Key quotes
· 3 pulledAccurate identification of immunogenic cancer epitopes remains a central challenge in immuno-oncology.
The Cancer Epitope Database and Analysis Resource (CEDAR) was developed to provide comprehensive curation of experimentally validated epitopes.
Recently, we released a suite of cancer-specific tools and analysis pipelines as part of the nextgen-tools.iedb.org platform, enabling users to generate, evaluate, and prioritize candidate T cell epitopes.
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