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First Greenland shark genome sequenced, revealing genetic secrets to 400-year lifespan and cancer resistance

By

Chris Simms

1d ago· 3 min readenNews

Summary

Scientists have completed the first whole-genome sequence of the Greenland shark, the longest-lived vertebrate species. The research reveals genetic adaptations related to DNA repair and cancer suppression that may explain their extreme longevity (potentially over 400 years) and resistance to age-related diseases. The findings could provide insights into aging and cancer mechanisms in humans.

Key quotes

· 3 pulled
The first-ever whole-genome sequence of a Greenland shark has revealed genetic clues to how the animals avoid cancer and live for hundreds of years.
The work may pave the way to a better understanding of age-related diseases in humans.
Greenland sharks (Somniosus microcephalus) typically grow to about 13 to 16 feet (4 to 5 meters) and live long lives in the North Atlantic and Arctic oceans.
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A genomic study of Greenland sharks, thought to be the longest-lived vertebrates on the planet, is hinting at the secrets to their epic lifespan and cancer resistance.

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