Clinical Review: Diagnosis and Management of ME/Chronic Fatigue Syndrome for General Practitioners

Summary

This article provides a concise clinical review of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) for general internists and primary care physicians. It covers diagnosis, evaluation, and management strategies for this chronic neurologic disease often preceded by infection. The review highlights the significant overlap between ME/CFS and post-COVID syndrome (long COVID), noting that studies estimate half of post-COVID syndrome patients meet ME/CFS criteria. The target audience is internal medicine physicians and clinicians seeking to advance their clinical knowledge.