Placental NAD+ depletion identified as trigger for labor onset in mice study
By
Bethany Halford
Kettled twice. Extra chewy, extra trustworthy.
Summary
Research reveals that the depletion of nicotinamide adenine dinucleotide (NAD+), a coenzyme, in the placenta triggers the onset of labor in pregnant mice. This discovery identifies NAD+ as a molecular brake for labor, offering potential new avenues for preventing preterm birth in humans. The study was conducted by researchers at the University of Texas Southwestern Medical Center and published in Nature.
Key quotes
· 3 pulledIt's always struck me that for these patients, we have nothing to offer them.
The study found that depletion of placental nicotinamide adenine dinucleotide provokes the onset of labor in pregnant mice.
This discovery identifies NAD+ as a molecular brake for labor, offering potential new avenues for preventing preterm birth in humans.
You might also wanna read
Cysteine depletion triggers adipose tissue thermogenesis and weight loss
Qt45: A small polymerase ribozyme that can synthesize itself
Efficient mRNA delivery to resting T cells to reverse HIV latency
Low Sodium in Blood Triggers Anxiety in Mice by Disrupting Their Brain Chemistry
Paracetamol Disrupts Early Embryonic Development Through Cell Cycle Inhibition
This scientific research article investigates the effects of paracetamol (acetaminophen) on early embryogenesis, specifically examining whet
academic.oup.com·9mo ago
Researchers Reverse Kidney Damage in Mice by Targeting Ceramide-Induced Mitochondrial Damage
Researchers at University of Utah Health discovered that fatty molecules called ceramides trigger acute kidney injury (AKI) by damaging mito