Molecular glue approach doubles survival time for pancreatic cancer patients in breakthrough trial
By
Bloomberg
Lightly toasted, lightly seasoned, mostly correct.
Summary
Chemical biologist Gregory Verdine developed a novel approach to fighting cancer by using "molecular glues" to bind disease-causing proteins inside cells and mark them for destruction. Despite initial skepticism, this approach led to a breakthrough drug for pancreatic cancer developed by Revolution Medicines Inc., which doubled typical survival time for patients with aggressive forms of the disease. The article covers the science behind molecular glues, the journey from academic research to clinical application, and the potential for this technology to become a major advancement in oncology.
Key quotes
· 2 pulledEverybody told us this is crazy, that it would never work.
One of the biggest advances in pancreatic cancer in decades came out of a crazy idea born in a Harvard University lab.
You might also wanna read
Spanish Researchers Develop Breakthrough Therapy Protocol for Pancreatic Cancer Treatment
Spanish researchers have developed a new therapy protocol that could revolutionize pancreatic cancer treatment. Pancreatic cancer is notorio
nypost.com·3mo ago
Daily pill daraxonrasib doubles survival in advanced pancreatic cancer, clinical trial shows
A clinical trial has shown that a daily pill called daraxonrasib can double survival time for patients with advanced pancreatic cancer, one
theguardian.com·21h ago
Engineered immunotherapy drug eliminates aggressive metastatic cancers in clinical trial
Researchers at Rockefeller University have developed an engineered CD40 agonist antibody that successfully eliminated aggressive metastatic
rockefeller.edu·8mo ago
CRISPR-Engineered Fat Cells Show Promise for Starving Cancer Tumors
Researchers at UC San Francisco have developed a novel cancer treatment approach using CRISPR-engineered fat cells to starve tumors. They tr
ucsf.edu·5mo ago