IAVI, Moderna, and Oxford develop three Ebola vaccines targeting Bundibugyo strain
By
James Gallagher
You can taste the rush. The dough hadn't risen.
Summary
Three organizations — IAVI, Moderna, and the University of Oxford — are developing vaccines targeting the Bundibugyo strain of Ebola amid growing outbreak concerns. IAVI uses a live but harmless engineered virus carrying the Ebola glycoprotein, while Moderna and Oxford use mRNA and genetic code delivery methods respectively to train the immune system to recognize and fight the virus.
Key quotes
· 4 pulledEach vaccine aims to train the body to spot the same structure on the surface of the virus – known as the Bundibugyo glycoprotein.
IAVI uses a live, but harmless virus that has been engineered so it also has the Ebola glycoprotein.
The mRNA vaccine and the Oxford vaccine both deliver a snippet of genetic code into the body.
Once inside it orders the construction of the Bundibugyo glycoprotein, which the body recognises as foreign and starts to attack.
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