The Vitamin B12 Paradox: Why Microbial Abundance Doesn't Prevent Human Deficiency
By
Sunil Kumar Dubey
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Summary
This article explores the paradox of vitamin B12: while microorganisms widely synthesize cobalamin, humans frequently suffer from deficiency. It examines the complex biology of B12, including its microbial production, human absorption mechanisms, and the reasons why deficiency persists globally despite microbial abundance. The article discusses food-based solutions and nutritional strategies to address this public health concern, highlighting the disconnect between microbial synthesis capacity and human nutritional outcomes.
Key quotes
· 3 pulledAlthough required only in trace amounts, disruptions in vitamin B12 homeostasis have profound systemic consequences, making its deficiency a persistent global nutritional concern.
Traditionally, vitamin B12 deficiency has been attributed to dietary insufficiency or impaired absorption.
Advances in microbiome research have revealed a more complex and intriguing dimension to cobalamin biology-one that challenges conventional understanding.
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