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Lynn Margulis's endosymbiotic theory: The paper rejected by 15 journals that revolutionized biology

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By Space Daily Editorial Team · Editorial process

17h ago· 7 min readenInsight

Summary

The article tells the story of Lynn Margulis, a young biologist whose groundbreaking 1967 paper on endosymbiotic theory — proposing that complex cells evolved through symbiotic mergers of simpler organisms — was rejected by 15 journals before finally being published. Despite initial ridicule, her theory that mitochondria and chloroplasts were once free-living bacteria that became incorporated into host cells is now a cornerstone of modern biology. The article explores how revolutionary scientific ideas often face fierce resistance before becoming accepted, and how Margulis's persistence reshaped our understanding of evolution and the very nature of life on Earth.

Key quotes

· 3 pulled
The idea was too speculative. The evidence was insufficient. The hypothesis was, according to some reviewers, simply too strange to be taken seriously.
She worked through a list of journals — the most prestigious, the most relevant, the most likely — and over the course of several years, she collected fifteen rejections.
The paper that explained why every living thing on Earth exists was rejected by 15 journals before anyone took it seriously — and the idea it contained is stranger than most science fiction
Snippet from the RSS feed
In 1966, a young biologist named Lynn Margulis submitted a paper to a scientific journal. It was rejected. She submitted it to another. Rejected again. She worked through a list of journals — the most prestigious, the most relevant, the most likely — and

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