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Predictive modeling of signal-responsive cis-regulatory elements in human red blood cell precursors

By

Dogiparthi, Venkatasai Rahul, Chee, Linda, Roy, Pooja, Zhou, Yichao, Rowley, M Jordan, Hewitt, Kyle J

1d ago· 38 min readenNews

Summary

This article presents a scientific study on predictive modeling of signal-responsive cis-regulatory elements in human red blood cell precursors. It focuses on how cis-elements coordinate with gene promoters to regulate signal-responsive transcriptional programs, which are turned on/off in response to cellular signals. The research involves computational modeling to predict these regulatory elements in erythroid precursor cells.

Key quotes

· 3 pulled
Signal-responsive transcriptional programs are turned on/off by cis-regulatory elements (cis-elements) acting in coordination with gene promoters
The research involves predictive modeling of cis-elements in human red blood cell precursors
This study focuses on understanding the regulatory mechanisms of gene expression in erythroid cells
Snippet from the RSS feed
Abstract. Signal-responsive transcriptional programs are turned on/off by cis-regulatory elements (cis-elements) acting in coordination with gene promoters

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