Review of Genetically Unmodified Cells as Drug Delivery Vehicles
By
Hongjun Li
Crusty in the right places. Worth the chew.
Summary
This scientific review article discusses the use of genetically unmodified cells as drug delivery vehicles. It highlights how cell-based drug delivery leverages natural cellular advantages such as prolonged circulation, tissue tropism, barrier crossing capabilities, and immune compatibility to improve drug biodistribution and prolong therapeutic exposure. The authors, affiliated with Zhejiang University, explore the potential of using native (non-genetically modified) cells for therapeutic delivery applications.
Key quotes
· 3 pulledCell-based drug delivery uses living cells' advantages, including prolonged circulation, tissue tropism, barrier crossing, and immune compatibility
Genetically Unmodified Cells for Drug Delivery and Therapy
State Key Laboratory of Advanced Drug Delivery and Release Systems, Liangzhu Laboratory, School of Pharmacy, Zhejiang University
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