PhD intern Sam Moix on drug target prioritisation and reproducible research at Open Targets
By
@embo.org
Baker's choice. Dense with flavour, light on filler.
Summary
A PhD candidate in Computational Biology at the University of Lausanne shares his three-month internship experience with the Open Targets core team in Hinxton. The article focuses on his work in drug target prioritisation, estimating drug perturbation profiles from large-scale biobank data, and the challenges of translating genetic evidence into insights for drug safety. It highlights learning about large-scale data processing, reproducible research workflows, and human genetics within a team at the forefront of biomedical data integration.
Key quotes
· 3 pulledMy time at Open Targets, working with a team at the forefront of large-scale biomedical data integration, was both scientifically and personally rewarding.
I learned a great deal about large-scale data processing, reproducible research, human genetics, and the challenges of translating genetic evidence into biologically meaningful insights for drug safety.
My work focuses on drug target prioritisation and on estimating drug perturbation profiles from large-scale biobank data.
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