Chromatin rewiring of β-globin and MYC enhancers by TGF-β1 drives defective erythropoiesis
3h ago
Study reveals TGF-β1 rewires β-globin and MYC enhancers, disrupting erythropoiesis. Higher levels correlate with anemia in myelodysplastic syndromes. Thoughts? PMID:42129196, Nat Commun 2026, @NatureComms #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪
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