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Daraxonrasib drug nearly doubles survival in advanced pancreatic cancer, oncologist reports

By

Christopher Lieu, MD

5h ago· 4 min readenInsight

Summary

Pancreatic cancer has extremely low survival rates (97% mortality within 5 years for metastatic cases) due to lack of effective screening and late symptom onset. The article discusses daraxonrasib, a breakthrough drug that nearly doubles survival for advanced pancreatic cancer patients, overcoming what was previously considered an 'undruggable' disease. An oncologist explains how this targeted therapy works against KRAS mutations, which are common in pancreatic cancer.

Key quotes

· 3 pulled
For patients who were diagnosed with metastatic pancreatic cancer between 2015 and 2021, about 97% died within five years of their diagnosis.
Pancreatic cancer is so deadly in part because there are no effective screening tests, and it rarely causes noticeable symptoms in its earliest stages.
By the time a patient experiences signs, such as jaundice – a yellowing of the skin – or abdominal pain, the cancer has often already spread to other organs.
Snippet from the RSS feed
Breakthrough drug nearly doubles survival with advanced pancreatic cancer – an oncologist explains how daraxonrasib overcame an ‘undruggable’ disease

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