Study reveals histamine neurons regulate moment-to-moment memory accessibility in mice
By
Nagoya City UniversityJun 11 2026
A second-rack bagel that's nearly first-rack. Tasty stuff.
Summary
Researchers at Nagoya City University, led by Professor Hiroshi Nomura, have identified that slow spontaneous fluctuations in brain histamine neurons control moment-to-moment memory accessibility. The study in mice showed that when histamine neuron activity was high just before a memory cue, the mice were more likely to express the memory. This neural mechanism may explain why the same memory can feel vivid and accessible one moment yet inaccessible the next, even when the memory itself remains intact.
Key quotes
· 3 pulledThe same memory can feel vivid and accessible one moment, yet stubbornly out of reach the next - even when the memory itself remains intact.
Slow spontaneous fluctuations in brain histamine neurons help control moment-to-moment memory accessibility.
When histamine neuron activity was high just before a memory cue, mice were more likely to express a memory.
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