Base editing in human embryos corrects some mutations but introduces others, preprint shows
By
Max Barnhart
Crackling crust, pillowy middle. The kind of bagel that earns a second cup of coffee.
Summary
A preprint released by geneticist Dieter Egli and collaborators at Columbia University demonstrates the use of base editing in human embryos. The work reveals that while base editing can correct some genetic mutations, it also introduces unintended mutations, proving that embryo editing is far from being a clinical reality. The experiment has sparked controversy regarding the ethical and safety implications of editing human embryos.
Key quotes
· 3 pulledOn June 1, an international group of industry and academic collaborators, led by geneticist Dieter Egli at Columbia University, released a preprint on bioRxiv demonstrating the use of base editing in human embryos.
The work proves that embryo editing is far from being a clinical reality.
But the experiment has sparked controversy nonetheless.
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